Thermo Fisher Scientific SCYL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 460-740 of human SCYL1 (NP_0657313) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SCYL1,uniProtId:Q96KG9-1,ncbiNodeId:9606,antigenRange:460-740,antigenLength:808,antigenImageFileName:PA5-93185_SCYL1_Q96KG9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93185_SCYL1_Q96KG9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.92 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806662

Product Specific Information

Immunogen sequence: SASTRHRVLT SAFSRATRDP FAPSRVAGVL GFAATHNLYS MNDCAQKILP VLCGLTVDPE KSVRDQAFKA IRSFLSKLES VSEDPTQLEE VEKDVHAASS PGMGGAAASW AGWAVTGVSS LTSKLIRSHP TTAPTETNIP QRPTPEGVPA PAPTPVPATP TTSGHWETQE EDKDTAEDSS TADRWDDEDW GSLEQEAESV LAQQDDWSTG GQVSRASQVS NSDHKSSKSP ESDWSSWEAE GSWEQGWQEP SSQEPPPDGT RLASEYNWGG PESSDKGDPF A; Positive Samples: HeLa, Mouse pancreas; Cellular Location: Cytoplasm, Endoplasmic reticulum-Golgi intermediate compartment, Golgi apparatus, Nucleus, centrosome, cis-Golgi network, cytoskeleton, microtubule organizing center

Target Information

With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms` tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.