Thermo Fisher Scientific SCYL1 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
SASTRHRVLT SAFSRATRDP FAPSRVAGVL GFAATHNLYS MNDCAQKILP VLCGLTVDPE KSVRDQAFKA IRSFLSKLES VSEDPTQLEE VEKDVHAASS PGMGGAAASW AGWAVTGVSS LTSKLIRSHP TTAPTETNIP QRPTPEGVPA PAPTPVPATP TTSGHWETQE EDKDTAEDSS TADRWDDEDW GSLEQEAESV LAQQDDWSTG GQVSRASQVS NSDHKSSKSP ESDWSSWEAE GSWEQGWQEP SSQEPPPDGT RLASEYNWGG PESSDKGDPF A

Positive Samples: HeLa, Mouse pancreas
Cellular Location: Cytoplasm, Endoplasmic reticulum-Golgi intermediate compartment, Golgi apparatus, Nucleus, Centrosome, Cis-Golgi network, Cytoskeleton, Microtubule organizing center

Target Information

Chromosome 11 contains approximately 135 million base pairs and around 1,400 genes, accounting for about 4% of human genomic DNA. It is gene- and disease-association dense. The Atm gene on chromosome 11 regulates cell cycle arrest and apoptosis following double-strand DNA breaks; mutations cause ataxia-telangiectasia. HBB gene mutations result in sickle cell anemia and β-thalassemia. WT1 gene mutations are linked to Wilms’ tumor, WAGR syndrome, and Denys-Drash syndrome. Other disorders associated with chromosome 11 include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.