Thermo Fisher Scientific GPHN Monoclonal Antibody (OTI7B6), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton through high-affinity binding to receptor subunit domains and tubulin dimers.
In non-neuronal tissues, it is also required for molybdenum cofactor biosynthesis.
Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, though full-length sequences of all variants are not yet known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.