Thermo Fisher Scientific GBP5 Monoclonal Antibody (OTI8B12), TrueMAB
인간 GBP5 단백질을 인식하는 마우스 단일클론 항체로, Western blot과 유세포분석에 최적화되어 있습니다. 동결건조 형태로 제공되며, 고순도의 친화 크로마토그래피 정제 제품입니다. 연구용으로 면역반응 및 염증 관련 기작 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B12 |
| Immunogen | Full length human recombinant protein of human GBP5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
Guanylate-binding proteins (GBPs) are interferon-induced GTP-binding proteins involved in innate immunity against microbial and viral pathogens. Humans have seven GBPs (hGBP1–hGBP7).
Human GBP1 and GBP2 exhibit antiviral activity and regulate endothelial cell proliferation and invasion in response to interferon (IFN).
GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble, but not crystalline, inflammasome priming agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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