Thermo Fisher Scientific GPHN Monoclonal Antibody (OTI7C6), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers. In non-neuronal tissues, it is required for molybdenum cofactor biosynthesis.
Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, though the full-length nature of all variants is not fully known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.