Thermo Fisher Scientific PIP4K2A Monoclonal Antibody (OTI1B2), TrueMAB
인간 PIP4K2A 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, ICC/IF, Flow Cytometry에 적합. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로 신호전달 및 세포 기능 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B2 |
| Immunogen | Full length human recombinant protein of human PIP4K2A produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase, type II, alpha) is a lipid kinase that catalyzes phosphorylation of phosphatidylinositol-5-phosphate to form phosphatidylinositol-4,5-bisphosphate.
It plays an essential role in phosphoinositide signal transduction, regulating secretion, cell proliferation, differentiation, and motility.
PIP4K2A is implicated in beta-globin gene expression regulation and Hb H levels in alpha-thalassemic patients.
Associated diseases include B-Lymphoblastic Leukemia/Lymphoma With Hyperdiploidy and Bipolar Disorder.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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