Thermo Fisher Scientific GBP5 Monoclonal Antibody (OTI8D8), TrueMAB
인간 GBP5 단백질을 인식하는 마우스 단클론 항체로 Western blot, ICC/IF, Flow Cytometry에 적합합니다. 무보존제, 동결건조 형태이며 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능하며, GBP5 관련 선천면역 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D8 |
| Immunogen | Full length human recombinant protein of human GBP5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Guanylate-binding proteins (GBPs) are interferon-induced GTP-binding proteins involved in innate immunity against microbial and viral pathogens. Humans have seven GBPs (hGBP1–hGBP7). GBP1 and GBP2 exhibit antiviral activity and regulate endothelial cell proliferation and invasion in response to IFN. GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble, but not crystalline, inflammasome priming agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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