Thermo Fisher Scientific Phospho-Acetyl-CoA Carboxylase (Ser79) Recombinant Rabbit Monoclonal Antibody (RM270)
Phospho-Acetyl-CoA Carboxylase (Ser79)을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공합니다. Western blot 및 IHC(P) 적용 가능하며, lot 간 일관성이 우수합니다. Protein A 정제, PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RM270 |
| Immunogen | A phospho-peptide corresponding to human Phospho-Acetyl-CoA Carboxylase (Ser79) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2744989 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to larger rabbit immune repertoire
Target Information
Acetyl-CoA carboxylase (ACC) is a multifunctional enzyme system that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Two forms exist—ACC-alpha and ACC-beta—encoded by different genes. ACC-alpha is enriched in lipogenic tissues. Regulation occurs through both long-term (transcriptional and translational) and short-term (phosphorylation/dephosphorylation) mechanisms, as well as allosteric modulation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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