Thermo Fisher Scientific beta-2-Microglobulin Polyclonal Antibody, Biotin
Human beta-2-Microglobulin 인식 Biotin 결합 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용 가능. Rabbit IgG 기반으로 고순도 정제됨. 장기 보관 시 -20°C에서 안정적이며, 연구용으로 적합.
- 카탈로그번호
- 200-406-141xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific beta-2-Microglobulin Polyclonal Antibody, Biotin
Thermo Fisher Scientific beta-2-Microglobulin Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:500–1:3,000 |
| ELISA | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 1:1,000–1:5,000 |
| Dot blot (DB) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-Beta-2-Microglobulin Antibody was produced by repeated immunizations with beta-2-Microglobulin protein isolated from human urine. |
| Conjugate | Biotin |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl, 10 mg/mL BSA |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at 4°C prior to restoration.
- For extended storage, aliquot contents and freeze at -20°C or below.
- Avoid cycles of freezing and thawing.
- Centrifuge if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
Anti-beta-2-Microglobulin antibody is an IgG fraction purified from monospecific antiserum by a multi-step process including delipidation, salt fractionation, and ion exchange chromatography, followed by extensive dialysis.
Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Biotin, anti-Rabbit Serum, and purified beta-2-Microglobulin (Human Urine).
Cross-reactivity with beta-2-Microglobulin from other sources may occur but has not been specifically determined.
Target Information
Beta-2-microglobulin (B2M) is a 12–14 kDa protein that forms part of the MHC class I complex. It is associated with HLA Class I antigens and expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial and epithelial cells, but absent on erythrocytes.
It is also found free in plasma and shares homology with immunoglobulin constant regions, forming a predominantly beta-pleated sheet structure.
B2M is involved in antigen processing and presentation, TCR signaling, and CD8+ cell activation.
Encoded by the B2M gene on chromosome 15, mutations can cause hypercatabolic hypoproteinemia.
B2M levels serve as markers for renal function and as prognostic indicators in HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일은 본문 하단에 위치)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.