Thermo Fisher Scientific IRAK-M Recombinant Rabbit Monoclonal Antibody (SN64-07)
IRAK-M 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 최적화됨. HEK293 세포에서 발현되며 높은 특이성과 재현성을 제공. 단백질 A로 정제된 액상 항체로 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN64-07 |
| Immunogen | Synthetic peptide within Human IRAKM aa 547–596 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809549 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
IRAK3 (Interleukin-1 receptor-associated kinase 3) is a serine/threonine kinase and a member of the IRAK protein family, essential in Toll/IL-R immune signal transduction.
It is mainly expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling.
IRAK3 plays a critical role in innate immunity and is linked to immunocompromised states during sepsis and susceptibility to asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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