Thermo Fisher Scientific Phospho-Aurora A/B/C (Thr288, Thr232, Thr198) Recombinant Rabbit Monoclonal Antibody (AuroraABC-CC12), PE
인간 Aurora A/B/C 인산화 상태(Thr288, Thr232, Thr198)를 인식하는 재조합 토끼 단일클론 항체. PE 형광 표지로 유세포분석(Flow Cytometry)에 적합. 고순도 Protein A/G 정제, 안정적 PBS/BSA 완충액 저장. 연구용으로만 사용 가능.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | AuroraABC-CC12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding human Aurora A (Thr288), Aurora B (Thr232), Aurora C (Thr198) |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897087 |
Additional Formats
Target Information
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a key regulator of mitosis.
The CPC ensures correct chromosome alignment and segregation, and is required for spindle assembly and cytokinesis.
Phosphorylates multiple substrates including BIRC5, CDCA8, INCENP, CENPA, DES, KIF2C, VIM, and histone H3 (Ser-10, Ser-28).
Involved in regulation of kinetochore localization, cytokinesis checkpoint, and p53 transcriptional activity.
Acts as a key regulator of active promoters in resting B- and T-lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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