Thermo Fisher Scientific INPP5J Polyclonal Antibody
INPP5J 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity Chromatography 정제 제품. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 60–360 of human INPP5J (NP_001002837.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855272 |
Product Specific Information
Immunogen sequence:
VTWNVGTAMP PDDVTSLLHL GGGDDSDGAD MIAIGLQEVN SMLNKRLKDA LFTDQWSELF MDALGPFNFV LVSSVRMQGV ILLLFAKYYH LPFLRDVQTD CTRTGLGGYW GNKGGVSVRL AAFGHMLCFL NCHLPAHMDK AEQRKDNFQT ILSLQQFQGP GAQGILDHDL VFWFGDLNFR IESYDLHFVK FAIDSDQLHQ LWEKDQLNMA KNTWPILKGF QEGPLNFAPT FKFDVGTNKY DTSAKKRKPA WTDRILWKVK APGGGPSPSG RKSHRLQVTQ HSYRSHMEYT VSDHKPVAAQ F
Target Information
Inositol and phosphatidylinositol phosphates are crucial for various cellular processes, including neuronal survival and signal transduction from growth factors, neurotransmitters, and G protein–coupled receptors.
INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP, PIB5PA, or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate.
It is expressed in lung, stomach, kidney, brain, small intestine, and heart, and localizes to membrane ruffles, where it may modulate inositol and phosphatidylinositol polyphosphate-binding proteins.
The INPP5J gene is located on human chromosome 22 and undergoes alternative splicing to produce three isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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