Thermo Fisher Scientific IL1RA Monoclonal Antibody (35730 (49/20))
Human IL1RA (CD121a) 인식하는 mouse monoclonal antibody로, Western blot 및 ELISA에 적합. IL1R1과 관련된 면역 및 염증 반응 연구용. 비결합형 액상 형태로, 고순도 affinity chromatography 정제 제품.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 35730 (49/20) |
| Immunogen | Recombinant peptide corresponding to the extracellular domain of human CD121a expressed in insect cell line Sf21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with <5% trehalose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2124907 |
Product Specific Information
This antibody does not react with rmIL-1 RI or rhIL-1 RII in either Western blot or ELISA applications.
Mouse anti-human CD121a, clone 35730, recognizes interleukin-1 receptor type 1 (IL1R1).
IL1RA/CD121a is widely expressed in various cell types including T cells and fibroblasts (Sims et al.) and is involved in the activation of NF-kappa-B (Slack et al.).
Target Information
The protein encoded by this gene is a cytokine receptor belonging to the interleukin 1 receptor family.
It acts as a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor type I (IL1R1/IL1RA).
This receptor mediates cytokine-induced immune and inflammatory responses.
The gene forms part of a cytokine receptor cluster along with IL1R2, IL1RL2, and IL1RL1, mapped to chromosome 2q12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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