Thermo Fisher Scientific BAIAP2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 362-521 of human BAIAP2 (NP_0593441) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAIAP2,uniProtId:Q9UQB8-1,ncbiNodeId:9606,antigenRange:362-521,antigenLength:552,antigenImageFileName:PA5-117010_BAIAP2_Q9UQB8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-117010_BAIAP2_Q9UQB8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.97 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901640

Product Specific Information

Positive Samples: A-549, K-562, SW620, 293T

Immunogen sequence: PRSSSMAAGL ERNGRMRVKA IFSHAAGDNS TLLSFKEGDL ITLLVPEARD GWHYGESEKT KMRGWFPFSY TRVLDSDGSD RLHMSLQQGK SSSTGNLLDK DDLAIPPPDY GAASRAFPAQ TASGFKQRPY SVAVPAFSQG LDDYGARSMS SGSGTLVSTV

Target Information

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.