Thermo Fisher Scientific Carbonic Anhydrase VB Polyclonal Antibody
Rabbit polyclonal antibody targeting Human Carbonic Anhydrase VB (aa 250-298). Validated for IHC and ICC/IF at 1:50–1:200 dilution. Affinity-purified with >95% purity. Suitable for research use in metabolic and mitochondrial studies.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 250–298 of Human Carbonic Anhydrase VB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719119 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity >95% (by SDS-PAGE).
Target Information
Carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They are involved in biological processes such as calcification, bone resorption, respiration, acid-base balance, and formation of aqueous humor, saliva, gastric juice, and cerebrospinal fluid.
CA VB (Carbonate Dehydratase VB) is one of two isoforms of CA V, localized to mitochondria and involved in metabolic processes. It is predominantly expressed in heart, pancreas, lung, placenta, kidney, and skeletal muscle. Unlike CA VA, CA VB is not expressed in the liver, suggesting distinct physiological roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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