Thermo Fisher Scientific Claudin 6 Polyclonal Antibody
Claudin 6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer(0.02% sodium azide) 내 1 mg/mL 농도. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 100–150 of Human Claudin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719121 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Tight junctions are a type of cell-to-cell adhesion found in epithelial and endothelial sheets, forming continuous seals around cells and serving as a barrier to prevent solutes and water from passing freely through the paracellular space. These junctions consist of continuous networking strands in the cytoplasmic leaflet with complementary grooves in the extracytoplasmic leaflet.
The Claudin 6 protein, encoded by this gene, is an integral membrane component of tight junction strands and functions as an entry cofactor for hepatitis C virus. Gene methylation may be associated with esophageal tumorigenesis. The CLDN6 gene is located adjacent to CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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