Thermo Fisher Scientific GPI Polyclonal Antibody
Thermo Fisher Scientific의 GPI Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, ICC/IF, ELISA에 적합합니다. Rabbit IgG 기반의 비결합 항체로, PBS 버퍼(50% 글리세롤) 내 액상 형태로 제공됩니다. 에너지 대사 관련 GPI 단백질 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–280 of human glucose-6-phosphate isomerase (NP_0001662) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805390 |
Product Specific Information
Immunogen sequence:
MAALTRDPQF QKLQQWYREH RSELNLRRLF DANKDRFNHF SLTLNTNHGH ILVDYSKNLV TEDVMRMLVD LAKSRGVEAA RERMFNGEKI NYTEGRAVLH VALRNRSNTP ILVDGKDVMP EVNKVLDKMK SFCQRVRSGD WKGYTGKTIT DVINIGIGGS DLGPLMVTEA LKPYSSGGPR VWYVSNIDGT HIAKTLAQLN PESSLFIIAS KTFTTQETIT NAETAKEWFL QAAKDPSAVA KHFVALSTNT TKVKEFGIDP QNMFEFWDWV GGRYSLWSAI
Positive Samples:
HL-60, BT-474, MCF7, HeLa, Mouse kidney, Mouse heart, Mouse brain, Rat brain, Rat heart
Cellular Location:
Cytoplasm
Target Information
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The encoded protein is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. It functions both inside and outside the cell: in the cytoplasm, it participates in glycolysis and gluconeogenesis; extracellularly, it acts as a neurotrophic factor for spinal and sensory neurons. Defects in this gene can cause nonspherocytic hemolytic anemia and severe enzyme deficiency may lead to hydrops fetalis, neonatal death, and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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