Thermo Fisher Scientific ETV1 Polyclonal Antibody
ETV1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 친화 크로마토그래피 정제, PBS/glycerol buffer, -20°C 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 80–300 of human ETV1 (NP_004947.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805388 |
Product Specific Information
Immunogen sequence:
AFHGLPLKIK KEPHSPCSEI SSACSQEQPF KFSYGEKCLY NVSAYDQKPQ VGMRPSNPPT PSSTPVSPLH HASPNSTHTP KPDRAFPAHL PPSQSIPDSS YPMDHRFRRQ LSEPCNSFPP LPTMPREGRP MYQRQMSEPN IPFPPQGFKQ EYHDPVYEHN TMVGSAASQS FPPPLMIKQE PRDFAYDSEV PSCHSIYMRQ EGFLAHPSRT EGCMFEKGPR Q
Target Information
ETV1 (Ets variant gene 1)
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins recognize this central core sequence but interact with unique flanking sequences. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'.
ER81 is highly expressed in brain, testis, lung, and heart, and moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 shows unique expression patterns suggesting an important role in organogenesis. ERK-1 activates ER81 transcriptional activity, while MAPKAP kinase 2 inhibits it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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