Thermo Fisher Scientific GRB10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:100-1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 100 and 150 of human growth factor receptor-bound protein 10. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRB10,uniProtId:Q13322-1,ncbiNodeId:9606,antigenRange:100-150,antigenLength:594,antigenImageFileName:IHC-00614_GRB10_Q13322-1_Rabbit.svg,antigenImageFileNamePDP:IHC-00614_GRB10_Q13322-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.0 to 8.0, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Crab-eating macaque

Target Information

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.