Thermo Fisher Scientific GRB10 Polyclonal Antibody
GRB10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC 및 IHC(P) 실험에 적합하며, 인간 및 유인원 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로 안정적이며 연구용으로 사용 가능.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 100 and 150 of human growth factor receptor-bound protein 10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, and Crab-eating macaque based on 100% sequence identity
Target Information
GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus.
A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7.
GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly.
GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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