Thermo Fisher Scientific Seipin Polyclonal Antibody
Seipin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 IHC(P) 검증 완료. Human과 Mouse에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로 지질 대사 및 지방형성 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 78–107 of the N-terminal region of human BSCL2 (Seipin) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541121 |
Product Specific Information
This antibody is predicted to react with bovine based on sequence homology.
Target Information
The Seipin (BSCL2) gene encodes a protein located in the endoplasmic reticulum, important for lipid droplet morphology. Mutations in this gene are associated with congenital generalized lipodystrophy type 2 (Berardinelli-Seip syndrome), a rare autosomal recessive disorder characterized by near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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