Thermo Fisher Scientific ABCC8 Monoclonal Antibody (3G5)
Thermo Fisher Scientific의 ABCC8 단클론 항체(3G5)는 인간 ABCC8 단백질을 인식하는 Mouse IgG2a 항체로, Western blot 및 ELISA에 적합합니다. ATP-sensitive potassium 채널 연구 및 인슐린 분비 관련 질환 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G5 |
| Immunogen | ABCC8 (NP_000343, 611–710 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
SEFLSSAEIR EEQCAPHEPT PQGPASKYQA VPLRVVNRKR PAREDCRGLT GPLQSLVPSA DGDADNCCVQ IMGGYFTWTP DGIPTLSNIT IRIPRGQLTMTarget Information
The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes and are divided into seven distinct subfamilies.
This protein is part of the MRP subfamily involved in multidrug resistance and functions as a modulator of ATP-sensitive potassium channels and insulin release.
Mutations or deficiencies in this gene are linked to hyperinsulinemic hypoglycemia of infancy and non-insulin-dependent diabetes mellitus type II.
Alternative splicing variants have been observed, though not fully characterized.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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