Thermo Fisher Scientific SULT1A1 Monoclonal Antibody (1F8)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MELIQDTSRP PLEYVKGVPL IKYFAEALGP LQSFQARPDD LLISTYPKSG TTWVSQILDM IYQGGDLEKC HRAPIFMRVP FLEFKAPGIP SGMETLKDTP APRLLKTHLP LALLPQTLLD QKVKVVYVAR NAKDVAVSYY HFYHMAKVHP EPGTWDSFLE KFMVGEVSYG SWYQHVQEWW ELSRTHPVLY LFYEDMKENP KREIQKILEF VGHSLPEETV DFVVQHTSFK EMKKNPMTNY TTVPQEFMDH SISPFMRKGM AGDWKTTFTV AQNERFDADY AEKMAGCSLS FRSEL

Target Information

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens, and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of this superfamily (SULT1, SULT2, and SULT3) show selectivity to certain substrate compounds.
SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein localized in the cytoplasm and belongs to the sulfotransferase family. It functions as a homodimer expressed in brain, liver, skin, and lung tissue. SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters, playing a role in the elimination of various compounds from the body. Additionally, it may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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