Thermo Fisher Scientific Phospho-BMAL1 (Ser42) Polyclonal Antibody
BMAL1 단백질의 Ser42 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot 및 IHC(파라핀 절편)에서 사용 가능. 사람, 생쥐, 랫트 반응성. 액상 형태로 제공되며 -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARNTL (Accession O00327), corresponding to amino acid residues around phosphorylated Ser42. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816054 |
Product Specific Information
Antibody detects endogenous levels of BMAL1 only when phosphorylated at Ser42.
Target Information
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK.
This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythm-associated genes.
Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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