Thermo Fisher Scientific COX11 Polyclonal Antibody
COX11 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human, Mouse, Rat에 반응합니다. IHC(P)에서 1:50–1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 버퍼에 보관하며 연구용으로 적합합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 50–100 of Human COX11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718996 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Cytochrome c oxidase (COX) is the terminal enzyme in the electron transfer chain, functioning as a transmembrane proton pump that builds an electrochemical gradient with chemical energy from the reduction of O₂.
Cytochrome c oxidase assembly protein COX11 is an intracellular mitochondrial membrane protein necessary for the construction of an active COX complex.
COX11 contains a single transmembrane helix downstream of the N-terminal mitochondrial targeting sequence and a C-terminal Cu(I)-binding domain.
The assembly of COX requires the delivery of metal cofactors. Along with COX12 and SCO1/2, COX11 acts as a metal ion chaperone necessary for copper insertion into CuA and CuB redox-active copper centers of COX in eukaryotes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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