Thermo Fisher Scientific HCN4 Monoclonal Antibody (SHG 1E5)
HCN4 단백질을 검출하기 위한 Rat 모노클로날 항체로, Western blot 및 IHC(F/P) 분석에 적합합니다. 사람, 마우스, 랫트 시료에 반응하며 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | – |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000 | – |
| Flow Cytometry (Flow) | 1/50 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SHG 1E5 |
| Immunogen | Synthetic peptide sequence corresponding to residues S H G S L L L P P A S S P P P P Q V P Q R R G T P P L T P G R L T Q D L K L of HCN4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2120037 |
Product Specific Information
MA3-903 detects HCN4 from human, mouse, and rat samples.
It has been successfully used in Western blotting and immunohistochemistry procedures.
By Western blot, MA3-903 detects a ~132 kDa band representing HCN4.
The MA3-903 immunogen is a synthetic peptide sequence corresponding to residues S H G S L L L P P A S S P P P P Q V P Q R R G T P P L T P G R L T Q D L K L of HCN4.
MA3-903 clone SHG 1E5 is a rat monoclonal hybridoma. This antibody was produced by immunizing a rat, isolating the spleen cells, creating the hybridoma, and successively injecting these cells into a mouse to produce ascites.
Target Information
HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels.
HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, and neuronal plasticity.
HCN4 channels function as receptors for sour taste and are associated with pacemaker potential generation in the sinoatrial node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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