Thermo Fisher Scientific Histone H2B Polyclonal Antibody
Histone H2B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 생쥐, 랫트 시료에서 반응하며 Western blot에 최적. 항원 친화 크로마토그래피로 정제된 고순도 제품으로, 안정적인 액상 형태로 제공.
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Thermo Fisher Scientific Histone H2B Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:1,000
- Publications: Refer to RRID AB_2942934
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Histone H2B synthetic peptide (coupled to carrier protein) corresponding to amino acids from the N-terminal region of human histone H2B. This sequence is well conserved in most isoforms of rat and mouse histone H2B, and has low homology to other histone family members. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942934 |
Product Specific Information
This antibody detects a 15 kDa protein corresponding to the molecular mass of Histone H2B on SDS-PAGE immunoblots of human A431, Jurkat, HeLa, mouse C2C12, rat PC12, and A7r5 cells.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.
Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4).
These nucleosomes compact DNA into chromatin, limiting DNA accessibility to cellular machineries that require DNA as a template.
Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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