Thermo Fisher Scientific Phospho-Histone H4 (Tyr72) Polyclonal Antibody
Phospho-Histone H4 (Tyr72) 항체로 인간, 마우스, 랫트 시료에 반응. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS/BSA/glycerol 완충액에 보관하며 -20°C에서 안정적. 연구용 전용 제품으로 진단용 사용 불가.
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Thermo Fisher Scientific Phospho-Histone H4 (Tyr72) Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:1,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phospho-Histone H4 (Tyr-72) synthetic peptide (coupled to carrier) corresponding to amino acids surrounding Tyr-72 in human histone H4. This site is well conserved in rat and mouse histone H4, but the site is not found in other histone family members. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | ~1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942936 |
Product Specific Information
The antibody was cross-adsorbed to unphosphorylated histone H4 (Tyr-72) peptide before affinity purification using phospho-histone H4 (Tyr-72) peptide.
This antibody detects a 10 kDa* protein on SDS-PAGE immunoblots of human PC3 and A431 cells.
This reactivity is not observed after alkaline phosphatase dephosphorylation of histone H4.
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure of chromosomal fiber in eukaryotes.
Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a member of the histone H4 family.
Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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