Thermo Fisher Scientific VE-cadherin Monoclonal Antibody (55-7H1), Alexa Fluor 647
인간 VE-cadherin(CD144)을 인식하는 마우스 단클론 항체로 Alexa Fluor 647로 표지됨. Western blot, ICC/IF, 유세포분석 등에 적합. 액상 형태로 제공되며 4°C 암소 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 4 µL / 1×10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 55-7H1 |
| Immunogen | Human endothelial cells |
| Conjugate | Alexa Fluor™ 647 |
| Excitation / Emission Max | 650 / 671 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913078 |
Additional Formats
Product Specific Information
This antibody recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
Target Information
VE-cadherin is a member of the cadherin superfamily located in a six-cadherin cluster on the long arm of chromosome 16. It is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. It functions as a classic cadherin, mediating homophilic cell adhesion and playing a key role in endothelial cell cohesion and junction organization. An alternative splice variant has been described, but the full-length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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