Thermo Fisher Scientific Periostin Monoclonal Antibody (CL12087)
인간 Periostin 단백질을 인식하는 Mouse IgG2a 단일클론 항체. IHC(P) 및 ICC/IF에 적합하며, 1 mg/mL 농도의 액상 형태로 제공. Protein A로 정제되었으며, PBS(40% glycerol, 0.02% sodium azide) 완충액에 저장. 연구용으로만 사용 가능.
- 카탈로그번호
- MA544161
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL12087 |
| Immunogen | Recombinant protein corresponding to Human POSTN (Periostin, UniProt ID: Q15063-1, antigen range: 525–548, length: 836 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2926305 |
Product Specific Information
- Antibody solution should be gently mixed before use.
- Optimal concentrations and conditions should be determined by the user.
- Immunogen sequence: LTQPGDWTLF VPTNDAFKGM TSEE
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked, secreted protein that binds heparin and acts as a ligand for αVβ3 and αVβ5 integrins.
It functions as a cell adhesion molecule in preosteoblasts, promoting recruitment, spreading, and attachment.
Periostin is mainly found in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, and is upregulated in epithelial ovarian and breast cancers.
Its expression is increased by BMP2 and TGF-β1.
The protein contains a signal sequence, a cysteine-rich domain, four fasciclin-like repeated domains, and a C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-44161_Periostin_Q15063-1_House_mouse.svg, MA5-44161_Periostin_Q15063-1_House_mouse_PDP.jpeg)
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