Thermo Fisher Scientific CD81 Monoclonal Antibody (M38), Alexa Fluor 488

Applications

Western Blot (WB)

• Assay-dependent

Immunohistochemistry (Paraffin) (IHC (P))

• Assay-dependent

Immunocytochemistry (ICC/IF)

• Assay-dependent

Flow Cytometry (Flow)

• 4 µL / 1×10^6 cells

Product Specifications

Additional Formats

• Unconjugated
• FITC
• PE
• Custom conjugation available

Product Specific Information

This antibody reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on the majority of cells.

Target Information

CD81 (TAPA-1) is a tetraspanin family protein expressed on most nucleated cells, especially germinal center B cells. It forms complexes with other tetraspanins, integrins, coreceptors, and MHC molecules, influencing adhesion, activation, proliferation, and differentiation of B and T cells.
In muscle tissue, CD81 promotes cell fusion and myotube maintenance. It also serves as a receptor for the hepatitis C virus.
CD81 associates with CD19, CD21, Leu 13, and integrins, and antibodies against CD81 show anti-proliferative effects on certain lymphoid cell lines. CD81 is located in a tumor-suppressor gene region and is a candidate for malignancy studies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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