Thermo Fisher Scientific CD81 Monoclonal Antibody (M38), Alexa Fluor 488
Alexa Fluor 488으로 표지된 CD81 단일클론 항체로, 인간·고양이·토끼 시료에 반응합니다. WB, IHC, ICC/IF, 유세포분석에 사용 가능하며, 세포 표면 CD81 단백질 검출에 적합합니다. 액상형으로 4°C 암소 보관, 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunocytochemistry (ICC/IF)
- Assay-dependent
Flow Cytometry (Flow)
- 4 µL / 1×10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat, Human, Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | M38 |
| Immunogen | MOLT-4 (human T-ALL cell line) |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913064 |
Additional Formats
- Unconjugated
- FITC
- PE
- Custom conjugation available
Product Specific Information
This antibody reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on the majority of cells.
Target Information
CD81 (TAPA-1) is a tetraspanin family protein expressed on most nucleated cells, especially germinal center B cells. It forms complexes with other tetraspanins, integrins, coreceptors, and MHC molecules, influencing adhesion, activation, proliferation, and differentiation of B and T cells.
In muscle tissue, CD81 promotes cell fusion and myotube maintenance. It also serves as a receptor for the hepatitis C virus.
CD81 associates with CD19, CD21, Leu 13, and integrins, and antibodies against CD81 show anti-proliferative effects on certain lymphoid cell lines. CD81 is located in a tumor-suppressor gene region and is a candidate for malignancy studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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