
Thermo Fisher Scientific SMN1 Recombinant Rabbit Monoclonal Antibody (9N9Q6)
SMN1 단백질 검출용 재조합 토끼 단클론 항체로 Western blot, IHC, ELISA에 적합. 인간 및 랫트 반응성. 고순도 Affinity Chromatography 정제. 안정적 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9N9Q6 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 103–200 of human SMN1 (Q16637) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912077 |
Product Specific Information
- Positive test controls: HeLa, HepG2
- Immunogen sequence:
SEDGCIYPAT IASIDFKRET CVVVYTGYGN REEQNLSDLL SPICEVANNI EQNAQENENE SQVSTDESEN SRSPGNKSDN IKPKSAPWNS FLPPPPPM
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This region contains multiple genes and repetitive elements, making it prone to rearrangements and deletions. The telomeric and centromeric copies encode the same survival motor neuron (SMN) protein. The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins, essential components of the spliceosome. Mutations in SMN1 are associated with spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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