Thermo Fisher Scientific AKT3 Monoclonal Antibody (9A5.H9.G7), PE

Applications and Tested Dilution

Product Specifications

Available Formats

• Unconjugated
• APC
• Biotin
• FITC
• Custom conjugation available upon request

Product Specific Information

• Store vial at 4°C prior to restoration.
• Restore with deionized water (or equivalent).
• Stable at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• Centrifuge product if not completely clear after standing at room temperature.
• Do not freeze after reconstitution.
• Store reagent in the dark and handle under subdued lighting.

Anti-AKT3 antibody is directed against human AKT3 and detects both unphosphorylated and phosphorylated forms of the protein.
Cross-reactivity with AKT3 from other species has not been determined, but the immunogen sequence shows 100% identity to human, mouse, and rat, suggesting expected cross-reactivity.
Cross-reactivity with AKT2 and AKT has not been determined.

Target Information

AKT3 (PKB gamma) is stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
It is involved in multiple biological processes including:

• Cell proliferation and differentiation
• Apoptosis and tumorigenesis
• Glycogen synthesis and glucose uptake

Alternative splice variants encoding distinct isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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