Thermo Fisher Scientific MOG Monoclonal Antibody (CL2858)
MOG 단백질을 표적으로 하는 CL2858 클론의 Mouse IgG1 단일클론 항체. Western blot 및 IHC(Paraffin) 실험에 적합. Human, Mouse, Rat 반응성. Protein A 정제, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL2858 |
| Immunogen | Recombinant protein corresponding to Human MOG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637260 |
Product Specific Information
- Immunogen sequence:
ALVGDEVELP CRISPGKNAT GMEVGWYRPP FSRVVHLYRN GKDQDGDQAP EYRGRTELLK DAIGEGKVTL RIRNVRFSDE GGFTCFFRDH SYQEEAAMEL KVEDPFYWVS PG - Highest antigen sequence identity:
- Mouse: 91%
- Rat: 89%
- Binds to an epitope within the peptide sequence GMEVGWYRPP as determined by overlapping synthetic peptides.
Target Information
The MOG gene encodes a membrane protein localized on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. It serves as a primary target antigen in immune-mediated demyelination and may play a role in myelin sheath maintenance and cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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