Thermo Fisher Scientific Plasminogen Monoclonal Antibody (5H3)
인간 Plasminogen 단백질을 인식하는 Mouse IgG1 단일클론 항체입니다. ELISA, IHC, Affinity Purification 등 다양한 응용에 사용 가능합니다. 액상 형태로 제공되며 4°C에서 보관합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Plasminogen Monoclonal Antibody (5H3)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- ELISA: Assay-dependent
- Affinity Purification (AP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H3 |
| Immunogen | Purified, full length, native human plasminogen protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 8.2 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_560663 |
Product Specific Information
MA1-20078 detects plasminogen in human samples.
Target Information
Plasminogen is a plasma protein synthesized mostly in the liver. It consists of a single polypeptide chain and has a molecular weight of 88.5 kDa. The plasma concentration is usually in the range of 70–200 mg/L.
Plasminogen is activated by tissue-plasminogen activator, urokinase, and streptokinase to form plasmin. Activation results from the cleavage and release of the preactivation peptide.
Plasmin consists of a heavy (A-) chain containing 5 kringles and a light (B-) chain with the active site. Plasmin is a trypsin-like protease whose natural substrate is fibrin, with binding sites for fibrin residing on the kringles.
Plasmin is essential for fibrinolysis, and decreased fibrinolytic potential due to congenital defects in plasmin can lead to recurring thrombosis, thrombophlebitis, and pulmonary embolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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