Thermo Fisher Scientific WDR74 Monoclonal Antibody (OTI3D10), TrueMAB
인간 WDR74 단백질을 인식하는 Mouse monoclonal 항체입니다. Western blot에 최적화되어 있으며, 동결건조 형태로 제공됩니다. PBS 완충액(8% trehalose) 기반으로 안정성이 높습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D10 |
| Immunogen | Human recombinant protein fragment (aa 114–385 of human WDR74) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The yeast nucleolar protein NOP7 is essential for the maturation of 66S preribosomes and interacts with multiple proteins. One such protein, the conserved WD repeat protein NSA1, is required for 66S ribosome assembly and is associated with the AAA ATPase Rix7. Release of NSA1 from late nucleolar pre-60S complexes requires Rix7 function. NSA1 upregulation in mammalian cancer cells suggests a potential role in cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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