Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI6B7), TrueMAB

Applications and Tested Dilution

Product Specifications

Additional Formats

• Biotin
• Request custom conjugation

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CD4 antigen recognizes MHC class II molecules and acts as a co-receptor for HIV. It is mainly expressed in T helper cells and other immune cells including monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 is found in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 is crucial for early T-cell activation via interaction with the T-cell receptor complex and Lck kinase, and may mediate neuronal damage in infectious and immune-related CNS diseases.
Multiple alternatively spliced transcripts have been reported (RefSeq, July 2017).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.