Thermo Fisher Scientific CD1.1 Monoclonal Antibody (CB3), Biotin

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1 µg/10^6 cells

-

Product Specifications

Species Reactivity

Chicken

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

CB3

Immunogen

Lymphocytes from the bursa of Fabricius of outbred chickens

Conjugate

Biotin Biotin Biotin

View additional formats

• Unconjugated
• FITC
• Request custom conjugation

Form

Liquid

Concentration

0.5 mg/mL

Purification

purified

Storage buffer

PBS, pH 7.4, with proprietary stabilizer

Contains

<0.1% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2745723

Target Information

CD1.1 molecules, like MHC I and II, play an important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. The chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. Two proteins have been identified - CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells and CD8 alpha+ cells. CD1.2 is expressed in TCR gamma delta cells but is nearly undetectable in TCR alpha beta. The monoclonal antibody CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.