Thermo Fisher Scientific Bu-1b Monoclonal Antibody (5-11G2), FITC

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1 µg/10^6 cells

Product Specifications

Additional Formats

• Unconjugated (Cat. No. MA5-28759)
• Biotin (Cat. No. MA5-28756)
• PE (Cat. No. MA5-28758)
• Custom conjugation available upon request

Target Information

Bu-1b, a product of the Bu-1b allele, is expressed on the cell surface as a disulfide-linked homodimer.
In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on:

• 85–90% of bursal cells
• 2–8% of thymocytes
• 15–27% of spleen cells
• 2–18% of peripheral blood cells

It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes.
In chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion.
The monoclonal antibody 5-11G2 reacts with lymphoid cells from CHA and H.B14Ab strains but does not react with cells from H.B14Aa.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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