Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI7C5), TrueMAB
인간 RAD23B 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. PBS buffer(8% trehalose)로 안정화되어 있으며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The RAD23B protein is one of two human homologs of Saccharomyces cerevisiae Rad23, which participates in nucleotide excision repair (NER).
It complements the NER defect in xeroderma pigmentosum group C (XP-C) cell extracts and interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition during base excision repair.
The N-terminal ubiquitin-like domain interacts with the 26S proteasome, implicating RAD23B in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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