Thermo Fisher Scientific MMP11 Recombinant Rabbit Monoclonal Antibody (SN74-08)
MMP11 단백질을 인식하는 recombinant rabbit monoclonal antibody로, Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 높은 특이성과 재현성을 제공하며, Protein A 정제 및 animal origin-free 포뮬레이션. 인체, 마우스, 랫드 반응성 확인.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:5,000 | - |
| Immunocytochemistry (ICC/IF) | 1:500–1:1,000 | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN74-08 |
| Immunogen | Synthetic peptide within Human MMP11 aa 439–488 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809570 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to a larger rabbit immune repertoire
Target Information
Stromelysin (MMP-11) is a member of the matrix metalloproteinase family with broad substrate specificity, capable of degrading proteoglycan, fibronectin, laminin, casein, and nonhelical regions of collagen.
The stromelysin-3 (MMP-11) gene is expressed specifically in stromal cells surrounding invasive breast carcinomas and localized to chromosome 22. MMP-11 expression is more frequently observed in malignant tumors than in benign ones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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