Takara Monitoring the immune response to viral infection

Monitoring the Immune Response to Viral Infection

During viral pandemics, next-generation sequencing (NGS) can be a valuable tool to help researchers and clinicians understand immune response to infection and treatments. Takara offers a variety of RNA-sequencing kits providing unmatched sensitivity and reproducibility for demanding sequencing applications, including COVID-19 research.

Understanding Host Immune Response

To analyze host response when a virus enters the body and after treatment administration, it is crucial to understand how transcriptional profiling of host cells changes.
For SARS-CoV-2, in particular, monitoring B cells and T cells helps clarify immune system dynamics. Key questions include:

• Are there changes in clonotype numbers?
• What clonotypes are present?
• How does infection affect clonotype diversity?
• How does treatment alter clonotype diversity?

Takara’s Human BCR Profiling Kit for Illumina Sequencing, Human TCRv2 Profiling Kit for Illumina Sequencing, and Cogent NGS Immune Profiler Software enable comprehensive immune repertoire analysis.
These tools help researchers answer critical questions and prepare for future viral challenges.

Overview

For additional product information and a full listing of available sizes, please visit:

• SMARTer Human BCR Profiling Product Page
• SMARTer Human TCRv2 Profiling Product Page
• SMARTer Human scTCR Profiling Product Page
• Cogent NGS Immune Profiler Software
• SMARTer Human scTCR Demultiplexer

Additional Product Information

Please refer to the product’s Certificate of Analysis for details on:

Certificates of Analysis and Kit Components Lists are located under the Documents tab.