
Thermo Fisher Scientific CCL27 Polyclonal Antibody
Human CCL27 단백질을 인식하는 Goat Polyclonal Antibody로, WB, IHC(F), Neutralization에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 피부 관련 T세포 연구 및 CCR10 결합 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
| Neutralization (Neu) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human CCL27/CTACK (Phe25–Gly112) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576357 |
Product Specific Information
- In Western blots, less than 2% cross-reactivity with recombinant mouse CCL27/CTACK is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The CCL27 gene is part of the CC cytokine family located on chromosome 9p. These cytokines are secreted proteins involved in immunoregulatory and inflammatory processes, characterized by two adjacent cysteines.
CCL27 is chemotactic for skin-associated memory T lymphocytes and may mediate lymphocyte homing to cutaneous sites. It binds specifically to chemokine receptor 10 (CCR10).
Studies of the murine homolog suggest a key role in T cell-mediated skin inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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