Thermo Fisher Scientific PPAR alpha Polyclonal Antibody
PPAR alpha 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 ChIP assay에 사용 가능하며, Mouse, Rat, Human 등 다양한 종에 반응. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- View 1 publication
ChIP Assay (ChIP)
- Tested Dilution: Assay-dependent
- View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat, Human, Insect |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human PPAR alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.04 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792272 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (91%), Rat (88%), Dog (92%), Pig (92%), Rhesus Monkey (98%), Bovine (88%), Guinea pig (87%).
- Positive Control: Rat primary hepatocyte, mouse liver, mouse brain, mouse lung.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Peroxisome proliferators are non-genotoxic carcinogens that exert their effects through interaction with nuclear hormone receptors termed peroxisome proliferator activated receptors (PPARs). These ligand-dependent intracellular proteins stimulate transcription of specific genes by binding to DNA sequences upon activation.
PPARs are activated by compounds such as clofibric acid, nafenopin, WY-14,643, and certain fatty acids. They can induce transcription of acyl coenzyme A oxidase and cytochrome P450 (CYP450) A6 through specific response elements.
PPAR, like other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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