Thermo Fisher Scientific IL-2 Monoclonal Antibody (JES6-5H4), FITC, eBioscience

Thermo Fisher Scientific IL-2 Monoclonal Antibody (JES6-5H4), FITC, eBioscience

Applications and Tested Dilution

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 488
• APC
• APC-eFluor 780
• Biotin
• Brilliant UV 737
• eFluor 450
• Functional Grade
• PE
• PE-Cyanine7
• PE-eFluor 610
• PerCP-Cyanine5.5
• Request custom conjugation

Product Specific Information

The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and major immunoregulatory cytokine.

• Reported Applications: Intracellular staining and flow cytometric analysis
• Tested Applications: Intracellular staining and flow cytometric analysis (≤ 0.5 µg/test)
• Definition of test: Amount (µg) of antibody staining a cell sample in 100 µL final volume
• Recommended titration for optimal performance
• Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

Interleukin 2 (IL-2) is an immuno-modulatory cytokine crucial for proliferation of activated T cells, differentiation of B cells, NK cells, monocytes, and macrophages.
IL-2 signals through IL-2R, a heterotrimeric receptor complex sharing gamma chain with IL-4 and IL-7.
Monoallelic expression in mature thymocytes regulates precise gene expression.
Disruption of IL-2-like gene in mice causes ulcerative colitis-like disease, indicating its essential role in immune response.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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