
Thermo Fisher Scientific RORA Polyclonal Antibody
RORA 단백질을 인식하는 토끼 폴리클로날 항체로 Western blot에 최적화됨. 인간 및 생쥐에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ROR alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792218 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus tropicalis (100%), Bovine (100%)
- Positive controls: HeLa, HepG2, Molt-4, mouse brain, NIH-3T3
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain.
RORA binds either as a monomer or as a homodimer to the retinoic acid response element, regulating gene expression and controlling cell function.
It interacts with NM23-2, NM23-1, CDK7, NCOA3, and NCOA6 coactivators. RORA is expressed in mesenchymal stem cells derived from bone marrow and modulates bone matrix components.
It is widely expressed in most tissues. Chromosomal aberrations involving RORA may be associated with acute promyelocytic leukemia (APL).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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