Thermo Fisher Scientific CEA Monoclonal Antibody (26/5/1)
CEA (CEACAM5) 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, WB, IHC, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관이 권장됩니다. 연구용 전용 시약입니다.
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Thermo Fisher Scientific CEA Monoclonal Antibody (26/5/1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 4 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 1–2 µg/1×10⁶ cells |
| Flow Cytometry (Flow) | 1.2 µg/1×10⁶ cells |
| ELISA | 1:200–1:400 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 26/5/1 |
| Immunogen | Extracted protein of CEACAM5 (CD66e, UniProt ID: P06731-1, antigen range: 1–702) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073301 |
Product Specific Information
This antibody recognizes native human CEACAM5 protein expressed in transfected mammalian cells.
Target Information
CEA (Carcino Embryonic Antigen, CD66e) is synthesized during fetal development in the gut and re-expressed in intestinal carcinomas and various tumors. It belongs to the immunoglobulin supergene family and includes one N domain and six constant-like A and B domains.
Antibodies to CEA help identify the origin of metastatic adenocarcinomas and distinguish pulmonary adenocarcinomas (60–70% CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
CEA functions as a cell adhesion molecule found on leukocytes, epithelia, and endothelia, mediating homophilic and heterophilic interactions. It plays roles in tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune modulation.
Multiple transcript variants exist, though not all full-length sequences are defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명 예시: MA1-17766_CD66e_CEACAM5_P06731-1_House_mouse.svg, MA1-17766_CD66e_CEACAM5_P06731-1_House_mouse_PDP.jpeg)
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