Thermo Fisher Scientific CEACAM1/CEACAM5 Monoclonal Antibody (4/3/17)

Applications

Tested Dilution

Publications

Western Blot (WB)

4 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

1-2 µg/1x10^6 cells

-

Flow Cytometry (Flow)

1.2 µg/1x10^6 cells

-

ELISA (ELISA)

1:200-1:400

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4/3/17

Immunogen

Extracted protein of CEACAM5 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CEACAM1/CEACAM5,uniProtId:P06731-1,ncbiNodeId:9606,antigenRange:1-702,antigenLength:702,antigenImageFileName:MA1-17767_CEACAM1CEACAM5_P06731-1_House_mouse.svg,antigenImageFileNamePDP:MA1-17767_CEACAM1CEACAM5_P06731-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1073292

Product Specific Information

This antibody recognizes native human CEACAM1, 5 protein expressed in transfected mammalian cells.

Target Information

Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.