Thermo Fisher Scientific FPR2 Monoclonal Antibody (GM1D6)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1 µg/1x10^6 cells

-

Flow Cytometry (Flow)

1.2 µg/1x10^6 cells

-

ELISA (ELISA)

1:200-1:400

-

Product Specifications

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

GM1D6

Immunogen

cDNA encoding human FPRL1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2105325

Product Specific Information

This antibody recognizes native human FPRL1 protein expressed in transfected mammalian cells.

Target Information

Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.