Thermo Fisher Scientific Carbonic Anhydrase VB Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:300–1:10,000

ELISA

• Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CA5B.

Target Information

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide.
CAs show extensive diversity in their distribution and subcellular localization. They are involved in various biological processes, including calcification, bone resorption, respiration, acid-base balance, and the formation of aqueous humor, saliva, gastric juice, and cerebrospinal fluid.

CA VB, also known as carbonate dehydratase VB, is one of two isoforms of CA V. It localizes to the mitochondria and is involved in metabolic processes. CA VB is predominantly expressed in heart, pancreas, lung, placenta, kidney, and skeletal muscle. It exhibits highest homology with family member CA VA (the second isoform of CA V); however, unlike CA VA, it is not expressed in the liver, suggesting that it plays a significantly different physiological role.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-80395_Carbonic_Anhydrase_VB_Q9Y2D0-1_Rabbit.svg, PA5-80395_Carbonic_Anhydrase_VB_Q9Y2D0-1_Rabbit_PDP.jpeg)