
Thermo Fisher Scientific Carbonic Anhydrase IX Polyclonal Antibody
Human CAIX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. IHC(P) 및 ELISA에 적합하며, 보존제가 포함되지 않은 액상 형태. Hypoxia 관련 연구 및 CA IX 발현 분석에 유용. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:500–1:2,000
ELISA
- Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CAIX protein (Met1–Asp414) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787719 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human CAIX/CA9.
Target Information
Carbonic anhydrase (CA) is an enzyme that catalyzes the rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in mammalian tissues.
CA IX is one of the most hypoxia-inducible genes due to its stability and membrane localization. Carbonic anhydrases play a key role in pH regulation by controlling hydrogen ion (H⁺) flux. Under hypoxic conditions, inhibition of CA IX increases cell death, making CA IX a reliable histochemical marker of hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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